Patient receiving personalized mental health care

If antidepressants haven't been enough, you're not out of options.

About one in three people with depression don’t get full relief from standard antidepressants.

Spravato® (esketamine) is a nasal spray that works on the brain’s glutamate system, a completely different pathway than traditional antidepressants. Unlike oral medications, see a shift within days, not weeks.

A new approach to depression treatment.

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FDA-approved.

Spravato is the first and only FDA-approved esketamine nasal spray for treatment-resistant depression

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Covered by most insurance.

Because it’s FDA-approved, Spravato is covered by most major insurance plans, including Medicare

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Rapid-acting

Experience meaningful improvement within days, in some cases even under 24 hours

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Now available on its own

Spravato is FDA-approved for use alone or with oral antidepressants as of 2025.

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How It Works

Spravato is a nasal spray you self-administer in our office, under the supervision of our clinical team. Because it’s a powerful, fast-acting treatment, it’s provided through the Spravato REMS program — a safety standard that means it’s only given in certified settings like ours, with monitoring afterward.

What to Expect During Spravato Treatment

You self-administer the nasal spray in a comfortable, private space, guided by our team.

Step 3 of the Marpa Minds treatment process

After the procedure, you’ll be observed for two hours to monitor your blood pressure and well-being. Temporary dreamlike feelings are normal and supervised.

Step 4 of the Marpa Minds treatment journey

Because of the lingering effects, you’ll need someone to drive you home — you can’t drive yourself the rest of that day.

A typical schedule: twice weekly for the first month, then weekly, then spacing out to maintenance visits as you stabilize. We’ll map your exact plan at your consultation.

WHY CHOOSE OUR SPRAVATO TREATMENT

Spravato, done right.

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A REMS-certified, fully monitored setting.

Spravato can only be given in certified settings — and ours is built for it, with the safety, privacy, and monitoring this treatment requires.

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Overseen by a real psychiatric team.

We don’t just administer Spravato — we manage your whole mental-health picture, adjusting your plan as you progress.

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We handle the insurance side.

Our team verifies your benefits and manages the authorization process, so the coverage Spravato qualifies for actually reaches you.

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Part of a complete depression toolkit.

We also offer IV and IM ketamine and TMS, so if Spravato isn’t the right starting point, we have other proven paths — and can sequence them as needed.

Who It’s For

Spravato® may be right for you if…

  • You’re an adult who has tried other antidepressants without full relief
  • You want a proven, FDA-approved treatment for depression
  • Broad Insurance coverage matters to you
  • You’re able to come in for monitored sessions and arrange a ride home

A consultation is the only way to know for sure. Spravato isn’t right for everyone — certain blood-pressure and cardiovascular conditions, among others, need review first — which is why we always start with an evaluation.

Two routes, one goal.

Our solution comes in two treatment options. Both use related medication and share the same goal, helping relieve depression, with each delivered in a different way.

We'll help you find the option that's right for you.

esketamine nasal spray for anxiety

Spravato®

FDA-approved esketamine nasal spray. The route most often covered by insurance.

Get Started
Three-step treatment process illustration – Step 2

IM Ketamine

A simpler intramuscular injection. A flexible, streamlined option.

Explore IM ketamine →

Covered by insurance

Spravato is covered by most insurance plans. Our team helps you through the process.

Accepted Insurance Plans

Don’t see your plan? Reach out here.

Questions about getting started

Is Spravato covered by insurance?

For most people, yes. Because Spravato is FDAapproved, it’s covered by most major insurance plans, including Medicare. We verify your benefits and manage authorization before you begin.

How is Spravato different from IV or IM ketamine?

Spravato is esketamine — the FDAapproved, insurance-covered form of ketamine therapy, taken as a nasal spray. IV and IM ketamine are related treatments used off-label and typically paid out of pocket. All can help with depression; we’ll help you choose the right fit.

Do I have to be on another antidepressant to take Spravato?

Not anymore. As of 2025, Spravato is FDA-approved as a standalone treatment, so it can be used on its own or alongside an oral antidepressant.

How fast does it work?

Faster than traditional antidepressants for many people — often within days, and in studies some experienced improvement in as little as 24 hours. Results vary by person.

Why do I have to stay for two hours? Can I drive afterward?

The monitoring period is a required safety step for this treatment. You’ll relax with us while we make sure you’re feeling steady, and you’ll need someone to drive you home — no driving the rest of the day.

Do I need a referral?

No referral needed — just book a consultation to get started.

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A proven path forward starts with one conversation.

Book a consultation at our White Plains or Suffern location. We’ll check whether Spravato® is right for you — and verify your insurance — in one call.