Psychedelic therapy offers a new path for people who haven't found relief with traditional antidepressants. At Marpa Minds, we provide legal, evidence-based treatments including Spravato® and ketamine therapy, delivered under the care of our psychiatric team.
Traditional antidepressants can take weeks to work, if they work at all. For people living with treatment-resistant depression, waiting can feel impossible.
Psychedelic therapy works differently. Rather than relying on the same pathways as conventional medication, treatments like Spravato® and ketamine act on the brain's glutamate system to encourage new neural connections. Many people experience meaningful improvement far sooner than with traditional antidepressants, all within a carefully supervised medical setting.
Traditional antidepressants take weeks to adjust serotonin, while psychedelic therapies target glutamate, promoting fast neuroplasticity and often causing noticeable changes within days.
About one in three people with depression don't get full relief from standard antidepressants. Psychedelic therapies were specifically developed for this population — and clinical evidence backs their effectiveness for treatment-resistant depression.
Psychedelic-assisted therapy at Marpa Minds isn't self-experimentation. Every session takes place in our clinical environment, monitored by licensed medical professionals with the training to guide and support you throughout.
Spravato® is the only FDA-approved psychedelic. Ketamine has been used safely in medicine for decades. Together, they represent the legal, evidence-backed forms of psychedelic therapy available in the US today.
Psychedelic therapy at Marpa Minds combines proven medical treatments with expert psychiatric care. Every patient begins with a comprehensive evaluation so we can recommend the approach that's most appropriate for their symptoms, history, and goals.
You settle into a quiet, comfortable treatment room.
Your treatment is administered and monitored by our clinical team throughout the session.
Most sessions include a period of dreamlike or dissociative experience — this is normal, expected, and supervised.
Afterward, you rest until you feel steady. Because of lingering effects, you'll need someone to drive you home.
Psychedelic therapy at Marpa Minds is delivered by a real psychiatric practice — not a wellness retreat. Every treatment we offer is evidence-based, medically supervised, and clinically appropriate for you specifically.
We evaluate whether psychedelic therapy is right for you, monitor your progress, and manage your whole mental-health picture — not just the treatment itself.
Spravato®, IV ketamine, IM ketamine, TMS, and traditional psychiatry — we can sequence or combine what works for you, rather than fitting you to the one thing we happen to offer.
Spravato®, the only FDA-approved psychedelic, is covered by most major plans. We verify benefits and manage authorizations up front — so eligible patients get access without surprises.
A consultation is the only way to know for sure. Psychedelic therapy isn't appropriate for everyone. Certain heart, blood pressure, psychiatric conditions, substance use history, and pregnancy require careful review, which is why every treatment begins with a clinical evaluation.
Our solution comes in two treatment options. Both use related medication and share the same goal, helping relieve depression, with each delivered in a different way.
We'll help you find the option that's right for you.
FDA-approved esketamine nasal spray. The route most often covered by insurance.
Explore Spravato →
A simpler intramuscular injection. A flexible, streamlined option.
Explore IM ketamine →
IM ketamine for depression is typically not covered by insurance, so it’s usually a self-pay treatment — though it’s often more affordable than IV because it’s simpler to deliver.
We’ll walk you through exact pricing and any payment or package options before you begin, with no surprises. If insurance coverage matters most to you, ask us about Spravato® treatment, which is more often covered.
Psychedelic therapy uses compounds that alter perception and consciousness — like ketamine and esketamine (Spravato®) — to help treat conditions such as treatment-resistant depression. When delivered in a supervised clinical setting, psychedelic therapy has shown rapid, meaningful results for people who haven't responded to traditional antidepressants.
Scientifically, yes — ketamine is classified as a dissociative psychedelic, producing altered perception and consciousness at therapeutic doses. It's the most-studied psychedelic-adjacent medicine currently used in psychiatric practice for depression.
Yes. Spravato® (esketamine) is chemically related to ketamine and produces similar dissociative effects. It's the first — and currently only — FDA-approved psychedelic medicine, specifically approved for treatment-resistant depression.
Yes — for the specific compounds we offer. Spravato® is FDA-approved and legal nationwide. Ketamine is FDA-approved as an anesthetic and legally prescribed off-label by licensed physicians for depression. Psilocybin, MDMA, and LSD remain federally scheduled and are not legal for clinical treatment in most US states. .
These substances are not currently legal for clinical treatment in most US states. Research on them is progressing, and some (like MDMA-assisted therapy for PTSD) are in advanced FDA review. As legal psychedelic options expand, we'll evaluate them for our clinical program.
At clinical doses, in a supervised medical setting, both Spravato® and ketamine have strong safety records. We screen every patient carefully at consultation and monitor closely during and after every psychedelic therapy session.
Many patients experience a dreamlike or dissociative state during treatment — an altered sense of time, body, or perception. This is normal, expected, and supervised. It's very different from recreational or unsupervised psychedelic use.
No referral needed — just book a consultation to get started.
Free, 15-Minute Consult Call with our Intake Team
Insurance-covered Telehealth Evaluation with our Providers
We Attain Insurance Authorization from Your Health Plan
Start Your Spravato Treatments in Our Center
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